Angiolymphoid hyperplasia with eosinophilia is a distinct clinicopathological entity
characterized by proliferation of endothelial cells and lymphoid hyperplasia with germinal
centers, associated with varying degrees of lymphocyte, histiocyte, and numerous
eosinophil infiltration.
The authors experienced two cases of angiolymphoid hyperplasia with eosinophilia.
The first case was a 28-year-old female who had a slowly growing mass in the right
elbow. The second was a 39-year-old male having a painless soft tumor in the inguinal
region for 8 years. Marked eosinophilia (43%,30%) were noted in both cases. Microscopic
examination showed vascular proliferation, many well formed lymphoid follicles, and
extensive eosinophil infiltration together with fibrosis.4 discussion on its histogenesis and
its relationship to Kimura's disease, with literature review, was made.
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